Begin by preheating your grill. Set the grill to a medium/high heat allowing it to heat to about 450 degrees
While your grill is heating, season the fish
Drizzle each filet with the olive oil, making sure to generously coat the filets on all sides. This will help the fish not to stick to the grill
Next, season each side of each filet with salt and pepper (to taste), as well as the paprika, cayenne pepper, and garlic powder
Place the fish on the grill and let cook for about 5 minutes on each side. You’ll know it’s time to flip the fish when it easily releases from the grill grates
Let cook for another 5 minutes
Check for doneness by inserting a food thermometer into the thickest part of the filet. Cooked tilapia will have an internal temperature of 145 degrees Fahrenheit
Using a fish spatula, carefully remove the tilapia from the grill and serve. If desired, squeeze a wedge of fresh lemon or lime juice overtop and enjoy!